ALS Compendium

Title: Gluthathionylation potentiates bening superoxide dismutase 1 variants to the toxic forms associated with amyotrophic lateral sclerosis

Year Published: 2013

Observation: Unmodified SOD1 variants that shared similar dissociation constants with SOD1 WT had increased dissociation constants when glutathonylated

Comment: Dissociation of SOD1 dimers is enhanced by glutathionylation

Citation: Mcalary, L., Yerbury, J. J., & Aquilina, J. A. (2013). Gluthathionylation potentiates bening superoxide dismutase 1 variants to the toxic forms associated with amyotrophic lateral sclerosis, 1–6. doi:10.1038/srep03275

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