ALS Compendium

Title: Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord

Year Published: 2013

Observation: Integration deficient lentiviral vectors encoding eGFP showed 50% transduction efficacy in motor neurons in vitro and 20-40% in vivo

Comment: Integration Defficient Lentiviral Vectors could be efficient and safer tools for spinal cord transduction in future therapeutic strategies

Citation: Peluffo, H., Foster, E., Ahmed, S. G., Lago, N., Hutson, T. H., Moon, L., … Yáñez-Muñoz, R. J. (2013). Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord. Gene Therapy, 20(6), 645–57. doi:10.1038/gt.2012.78

Back to Homepage