ALS Compendium

Title: Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

Year Published: 2011

Observation: co-cultured MNs with sALS astrocytes. After 120h there were 45-70% fewer MNs compared to non ALS controls

Comment: Identify astrocytes as a non cell autonomous component in sALS

Citation: Haidet-phillips, A. M., Hester, M. E., Miranda, C. J., Meyer, K., Braun, L., Frakes, A., … Kaspar, B. K. (2011). Astrocytes from familial and sporadic ALS patients are toxic to motor neurons, 29(9). doi:10.1038/nbt1957

Back to Homepage