ALS Compendium

Title: Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

Year Published: 2011

Observation: TDP43 binds GU rich sequences. TDP43 regulates mRNA involved in neuronal development

Comment: TDP43 is important for the regulation of splicing in the brain

Citation: Tollervey, J. R., Curk, T., Rogelj, B., Briese, M., Cereda, M., Kayikci, M., … Ule, J. (2011). Characterizing the RNA targets and position-dependent splicing regulation by TDP-43. Nature Neuroscience, 14(4), 452–8. doi:10.1038/nn.2778

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