ALS Compendium

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention

Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival

Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS

Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels

C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes

A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology

Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models

Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons

Novel TARDBP mutations in Nordic ALS patients